Malignant Epithelial Edontogenic Ghost Cell Tumor in the Mandible and Tongue : A Case Report.

Gil, Minn Seok; Lee, Choong Jae; Lee, Se Il

Case Report

Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(2):296-299.
Published online March 1, 1999.

Malignant Epithelial Edontogenic Ghost Cell Tumor in the Mandible and Tongue : A Case Report.

Minn Seok Gil, Choong Jae Lee, Se Il Lee

Abstract

Benign odontogenic neoplasms are rare, but malignant odontogenic neoplasms are extremely rare. The majority of malignant epithelial neoplasms occurring in the jaws are the result of metastasis from distant primary neoplasms of direct invasion from contiguous carcinoma of the oral mucosa, sinus mucosa, salivary gland or skin. A few remaining primary intraosseous carcinoma of the jaw are presumed to be of mostly odontogenic origin since epithelial remnants of odontogenesis are numerous in the maxilla arts mandible. Although calcifying odontogenic cyst(COC) is a well-established pathologic entity, it has been recognized that there is an odontogenic neoplasm with histologic features similar to the COC(malignant epithelial odontogenic host cell tumor; EOGCT) that has been diagnosed as COC. Some authors have reported previously in the literature describing malignant EOGCT. We experienced one case of malignant EOGCT with aggressive growth pattern and histologic features strongly implying its malignant potential. The lesion was excised by anterior mandibular resection, total 1 resection of the tongue and bilateral functional neck dissection. The tongue was reconstructed by using the infrahyoid muscle neurovascular island flap and neurovascular radial forearm free flap. The mandible was reconstructed by using the osteocutaneous fibular free flap.