A Case of Kimura Disease on Parotid Gland.

Cha, Jin Han; Rhee, Seung Chul; Park, Heung Sik; Kang, Sora; Koo, Hea Soo; Lee, Soon Nam

Case Report

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2003;30(1):97-100.
Published online January 1, 2003.

A Case of Kimura Disease on Parotid Gland.

Jin Han Cha, Seung Chul Rhee, Heung Sik Park, Sora Kang, Hea Soo Koo, Soon Nam Lee

¹Department of Plastic and Reconstructive Surgery, Cosmetic Plastic Cener, Dongdaemoon Hospital, Ewha Womans University, Seoul, Korea. JINHAN57@chollian. net
²Department of Pathology, Dongdaemoon Hospital, Ewha Womans University, Seoul, Korea.
³Department of Internal Medicine, Dongdaemoon Hospital, Ewha Womans University, Seoul, Korea.

Abstract

Kimura disease(KD) is a chronic inflammatory disorder of unknown etiology and results from an abnormal proliferation of lymphoid follicles and vascular endothelium and rarely has been reported in Korea. Clinical findings of Kimura disease include solitary or multiple, firm, subcutaneous nodules, which usually are located on the head or neck but parotid region is the most common site. The clinical course of the disease is chronic, with lesions frequently persisting or recurring despite treatment. The prognosis for KD is good, with no potential for malignant transformation. Our case is a 45-years-old man who had huge mass on left cheek which had slowly grown since about 10 years before. We planned to perform superficial parotidectomy but the mass was poorly demarcated due to extensive fibrosis and adhesion and had easy bleeding tendency. After frozen biopsy, we performed tumor debulking operation followed by cyclosporin therapy by the dose of 2.5 mg/Kg/day. The lesion was almostly cleared successfully after 3 months later. We report important aspects of clinical findings, histologic features, and therapeutic options of the rare case of KD with review of the previous articles.

Keywords: Kimura disease; Parotid