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Journal of the Korean Society of Plastic and Reconstructive Surgeons 2002;29(6):571-574.
Published online November 1, 2002.
Benign Symmetrical Lipomatosis.
Sug Won Kim, Dong Wan Seo, Sung Joon Lee, Yoon Kyu Chung
Department of Plastic & Reconstructive Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea. swkim@wonju.yonsei.ac.kr
Benign symmetrical lipomatosis(BSL) is a rare disease of unknown origin characterized by symmetrical and diffuse deposits of nonencapsulated fatty tissue. It is located on the neck, the shoulder, the proximal regions of the extremities and the abdomen. It is strongly associated with alcoholism. Other associated diseases include liver disease, dyslipidemia, gout, abnormal glucose tolerance, and malignancies of the upper airways. BSL is found mainly in middle-age, mediterranean men. Imaging using either computed tomography or magnetic resonance imaging is often recommended. Dietary restriction provides no relief. Abstinence from alcohol may delay further progression but does not cause regression of the deformity. The only effective therapy for BSL is surgical removal but recurrence is common. Physicians should be aware of this condition because of its association with metabolic disease and malignancies
Keywords: Lipomatosis; Madelung's disease
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