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Journal of the Korean Society of Plastic and Reconstructive Surgeons 2008;35(3):333-336.
Published online May 1, 2008.
A Case of Primary Cutaneous Adenoid Cystic Carcinoma at the Genital Area.
Hoi Joon Jeong, Dae Gu Son, Sun Young Kwon
1Department of Plastic and Reconstructive Surgery, Keimyung University School of Medicine, Daegu, Korea. handson@dsmc.or.kr
2Department of Pathology, Keimyung University School of Medicine, Daegu, Korea.
Abstract
PURPOSE
Adenoid cystic carcinoma is a rare type of eccrine sweat gland carcinoma. Although it is mostly known as a neoplasm of the salivary gland, it could occur as a primary skin tumor. We present a patient with a primary cutaneous adenoid cystic carcinoma at the genital area. METHODS: A 60-year-old man had a slowly growing 1 cm sized single tender mass near the left scrotum and he underwent excisional biopsy at a local clinic. A diagnosis of adenoid cystic carcinoma was made and thus he was transferred to our hospital. In physical examination, other specific findings were not detected except a linear scar caused by a previous skin biopsy near the left scrotum. In CT scan, PET-CT scan and endoscopy, there was no evidence of neoplasm in other organs. It was diagnosed as the primary cutaneous adenoid cystic carcinoma and then wide excisions were performed including total 4.5cm margin of normal skin.
RESULTS
Microscopic findings revealed proliferation of tumor cell islands with cribriform or tubular patterns containing several round, pseudocystic structures. The tumor cells showed basaloid cells with uniform and small nuclei. Tumor cells infiltrated into the dermis and upper portion of subcutaneous tissue. There was multifocal perineural invasion of tumor cells. In postoperative 6 months, we found no recurrence and other complications.
CONCLUSION
Herein we found a rare case of primary cutaneous adenoid cystic carcinoma at the genital area.
Keywords: Adenoid cystic carcinoma; Skin; Genital
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