Malignant Peripheral Nerve Sheath Tumor of Scalp.

Lee, Ki Young; Bae, Joon Sung; Jun, Young Joon; Lee, Hee Jeong; Kim, Young Jin

Case Report

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2007;34(4):494-496.
Published online July 1, 2007.

Malignant Peripheral Nerve Sheath Tumor of Scalp.

Ki Young Lee, Joon Sung Bae, Young Joon Jun, Hee Jeong Lee, Young Jin Kim

¹Department of Plastic Surgery, College of Medicine, The Catholic University of Korea, Gyeonggi, Korea. yjkim@hfh.cuk.ac.kr
²Department of Pathology, College of Medicine, The Catholic University of Korea, Gyeonggi, Korea.

Abstract

PURPOSE
Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, usually arising from somatic soft tissues or peripheral nerves. Primary MPNST of the scalp is extremely rare. The case is being reported for its rarity. METHODS: A 53-year-old female was presented with a scalp mass on vertex area. The tumor was localized in scalp skin and did not invade underlying periosteum or skull and treated with complete surgical excision followed by adjuvant chemotherapy and radiotherapy.
RESULTS
Histologically, the tumor showed malignant spindle cells with focal S-100 positivity on immunohistochemistry and a diagnosis of MPNST was made.
CONCLUSION
Authors experienced a rare case of primary scalp MPNST and report the case.

Keywords: Malignant peripheral nerve sheath tumor (MPNST); Soft tissue sarcoma; Neurofibrosarcoma; Neurofibroma; Scalp mass