Malignant Transformation of Fibrous Dysplasia: A Case Report of Malignant Fibrous Histiocytoma of Facial Bone.

Lee, Sang Joon; Lim, So Young; Oh, Kap Sung; Bang, Sa Ik; Hyon, Won Sok; Mun, Goo Hyun

Case Report

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2007;34(3):403-405.
Published online May 1, 2007.

Malignant Transformation of Fibrous Dysplasia: A Case Report of Malignant Fibrous Histiocytoma of Facial Bone.

Sang Joon Lee, So Young Lim, Kap Sung Oh, Sa Ik Bang, Won Sok Hyon, Goo Hyun Mun

Department of Plastic and Reconstructive Surgery, Sungkyunkwan University School of Medicine, Seoul, Korea. pslisy@hanmail.net

Abstract

PURPOSE
Malignant degeneration of fibrous dysplasia is an uncommon recognized complication of this disease. Especially, degeneration of fibrous dysplasia to malignant fibrous histiocytoma(MFH) in facial bone is rare and the publications had been limited. The purpose of this report is to share our experience. METHODS: A 46-year-old patient with facial fibrous dysplasia visited our clinic for recent facial tingling and swelling. Malignant degeneration of fibrous dysplasia was suspected.
RESULTS
Total excision of the mass and adjacent facial bone was performed. Defect was immediately reconstructed with bone graft and bone cement. At a month follow up, metastasis was detected at ipsilateral parotid gland. Superficial parotidectomy and neck dissection was performed. The patient is currently taking chemotherapy.
CONCLUSION
Because of the uncommon presentation of this entity, clinical course of treatment was dependent on other histological types of malignant degeneration. We report this case to share our experience.

Keywords: Malignant fibrous histiocytoma; Malignant transformation; Facial bone; Fibrous dysplasia