Analysis of Necrotizing Fasciitis Patient by Causative Pathogens.

Park, Sun Hyung; Noh, Bok Kyun; Kim, Eui Sik; Hwang, Jae Ha; Kim, Kwang Seog; Lee, Sam Yong

Original Article

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2007;34(3):319-324.
Published online May 1, 2007.

Analysis of Necrotizing Fasciitis Patient by Causative Pathogens.

Sun Hyung Park, Bok Kyun Noh, Eui Sik Kim, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee

Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School, Gwangju, Korea. sylee@ jnu.ac.kr

Abstract

PURPOSE
Necrotizing fasciitis is a rapid progressive, life-threatening disease. Many organisms have been identified for causative pathogens of necrotizing fasciitis. And necrotizing fasciitis caused by Vibrio vulnificus is a matter of grace concern in Southwest seashore of Korea recently. But concrete analysis between these pathogens was not executed yet. METHODS: Sixty necrotizing fasciitis patients were included in this study. We divided the patients into 2 groups: Group A was the case which Vibrio vulnificus was cultured for causative pathogen of necrotizing fasciitis, and Group B was the case of other organisms. And we analysed each group for treatment, progression and prognosis.
RESULTS
There was no significant difference between two groups in total hospital stay but there was a great difference in ICU stay and progression to septic shock. Also, there was a great difference in mortality within 48 hours but there was no difference in mortality of 48 hours after hospital visit.
CONCLUSION
This indicates that intial management of necrotizing fasciitis cased by Vibrio vulnificus is the key of treatment. So initial medical management with early surgical intervention is necessary for necrotizing fasciitis.

Keywords: Necrotizing fasciitis