The Histological Change of Orbicularis Oculi Muscle according to the Age.

Ahn, Ki Young; Chang, Jae Hoon; Choi, Won Seok; Shin, Im Hee; Park, Jae Bok

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Original Article

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2006;33(1):87-94.
Published online January 1, 2006.

The Histological Change of Orbicularis Oculi Muscle according to the Age.

Ki Young Ahn, Jae Hoon Chang, Won Seok Choi, Im Hee Shin, Jae Bok Park

¹Department of Plastic and Reconstructive Surgery, School of Medicine, Daegu Catholic University, Daegu, Korea. kyahn@cu.ac.kr
²Department of Pathology, School of Medicine, Daegu Catholic University, Daegu, Korea.
³Department of Biomedical Statistics, School of Medicine, Daegu Catholic University, Daegu, Korea.

Abstract

This study is to investigate the patients who had blepharoplasty for cosmetic purposes or facial nerve disorders. 21 patients were examined with an age from 17 to 63 years. Sixteen cases were classified as a normal group for investigation of the histopathologic change according to the age. The rest were patients of Bell's palsy(2), Botox(R) injection(2) and blepharospasm (1). We measured a mean diameter of myofiber and dimension's proportion of muscluar tissue per regular visual field. First, we measured a statistical significance according to the age in normal cases by grouping them into younger than 30-year-old, 30's, 40's, 50's and 60's. Second, we divided normal cases(16) into Group A and B by two bases for statistical analysis. In conclusion, although there were several differences as vacuolation, internalization of sarcolemnic nuclei between 35-year-old and 62-year-old patients in simple comparison, there was no uniform decrease according to the age. There were also no significant statistical changes in the value of a diameter of myofibers and dimension's proportion of muscular tissue according to the age in any of the two normal groups. But in Botox(R) injection and Bell's palsy, blepharospasm patients, two values showed remarkable difference compared to the normal group of same age.

Keywords: Muscle atrophy; Facial nerve disorder; Aging process

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