Effectiveness of Vicryl plus(R)(Ethicon, USA) in Nosocomial Bacteria.

Jin, Young Wan; Na, Young Cheon

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Original Article

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2011;38(5):590-593.
Published online September 1, 2011.

Effectiveness of Vicryl plus(R)(Ethicon, USA) in Nosocomial Bacteria.

Young Wan Jin, Young Cheon Na

Department of Plastic and Reconstructive Surgery, Wonkwang University School of Medicine, Iksan, Korea. ycnadr@hanmail.net

Abstract

PURPOSE
Surgical site infections(SSIs) are the third most frequently reported nosocomial infection. Of these SSIs, mostly were confined to the incision associated with underlying disease as diabetes, cigarette smoking, systemic steroid use, obesity, operating room environment, suture and surgical technique. This study has been planned to reduce the SSIs by using Vicryl plus(R)(Ethicon, USA) which contains triclosan, a broad-spectrum antibacterial agent, into the infected wound to evaluate whether or not Vicryl plus(R)(Ethicon, USA) is effective to nosocomial bacteria using a zone of inhibition assay. METHODS: We did a comparison of Vicryl plus(R) suture(with triclosan) size 2-0, 5-0 with Vicryl(R) suture(without triclosan) size 4-0 each as treatment and control group, applied in Mueller-Hinton agar infected by following mircroorganisms: Methicillin-sensitive Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanii, Escherichia coli, Enterobacter faecalis, Pseudomonas aeruginosa, Candida albicans. Cultures were made of the selected mircroorganisms, seeding the study strain in agar plates for 24 and 48-hour period in an oven at 37degrees C followed by zone of inhibition assay.
RESULTS
Vicryl plus(R) group has demonstrated to create a zone of inhibition against MRSA, MSSA and A. baumanii, but no effect on E. faecalis, P. aeruginosa, C. albicans. Vicryl plus(TM) suture size 2-0 also had antibactericidal effect while Vicryl plus(R) suture size 5-0 did not. Vicryl(R) group had no zones of inhibition showing colonization at all mircroorganisms.
CONCLUSION
Our results seem to warrant the use of Vicryl plus(R) as absorbable buried suture when concerning SSIs as a prophylaxis against surgical nosocomial infection.

Keywords: Vicryl plus; Vicryl; Triclosan; Nosocomial infection

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