A Case of Nerve Sheath Myxoma on the Fingertip.

Lee, Yong Seok; Kim, Chul Han; Kang, Sang Gue; Tark, Min Seong

Original Article

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2010;37(1):67-70.
Published online January 1, 2010.

A Case of Nerve Sheath Myxoma on the Fingertip.

Yong Seok Lee, Chul Han Kim, Sang Gue Kang, Min Seong Tark

Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University, Seoul, Korea. kchann@hanmail.net

Abstract

PURPOSE
Nerve sheath myxoma is a rare cutaneous neoplasm originating from the peripheral nerve sheath and divided into three groups : myxoid, cellular and mixed type. There is a controversy on it's origin whether schwannian cell or perineurial differentiation, or anything else. Myxoid nerve sheath myxoma is asymptomatic, soft, papule or nodule in middle-age adults. We report a case of myxoid nerve sheath myxoma on the fingertip. METHODS: A 53-year-old woman presented with a painful, 0.4 x 0.4 x 0.6 cm sized, corn shaped nodule on the left 3rd fingertip. We put into surgical excision and studied it by histopathologically and specific immnohistochemical stain.
RESULTS
The tumor has well defined nodules separated by thin fibrous connective tissue with abundant myxoid stroma and were positively stainded for S-100 protein, NSE and GFAP. After surgical treatment it was healed without recurrence.
CONCLUSION
Nerve sheath myxoma is rare neoplasm and located mainly on face, but very rarely on the fingertip. We report a case of painful myxoid nerve sheath myxoma located on the 3rd fingertip.

Keywords: Nerve sheath myxoma