A Case Report of Palatoplasty in a Patient with Clotting Factor X Deficiency.

Kim, Suk Wha; Jeong, Eui Cheol; Yun, Byung Min; Choi, Tae Hyun; Kang, Hyoung Jin

Case Report

Journal of the Korean Society of Plastic and Reconstructive Surgeons 2009;36(6):792-794.
Published online November 1, 2009.

A Case Report of Palatoplasty in a Patient with Clotting Factor X Deficiency.

Suk Wha Kim, Eui Cheol Jeong, Byung Min Yun, Tae Hyun Choi, Hyoung Jin Kang

¹Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul, Korea. ejeong@kma.org
²Department of Plastic and Reconstructive Surgery, Korea University College of Medicine, Seoul, Korea.
³Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.

Abstract

PURPOSE
Clotting factor X deficiency is one of the least common coagulation disorders. The authors describe a case of cleft palate in a patient with a congenital clotting factor X deficiency. METHODS: In pediatric patients with a cleft palate, the coagulation problem is more worrisome, because they are more sensitive to blood than adults, and because postoperative bleeding can cause blood ingestion with subsequent vomiting, aspiration, and airway obstruction. To prevent hemorrhagic complications in the described case, fresh frozen plasma (FFP) was administered every 24 hours from the day before surgery to the second postoperative day.
RESULTS
Good hemostasis, normal healing, and no complications was shown postoperatively.
CONCLUSION
The replacement of fresh frozen plasma was useful in the case of congenital clotting factor deficiency for bleeding prophylaxis in cleft palate operation.

Keywords: Cleft palate; Clotting factor X deficiency; Bleeding prophylaxis